Edrophonium Challenge Test for Blepharospasm
نویسندگان
چکیده
منابع مشابه
Edrophonium Challenge Test for Blepharospasm
BACKGROUND Blepharospasm is typically diagnosed by excluding any secondary diseases and neuropsychiatric disorders, as specific tests for blepharospasm are currently unavailable. Since anticholinergic agents are used to improve the symptoms of dystonia, we hypothesized that edrophonium chloride, an acetylcholinesterase inhibitor, may make the symptoms of dystonia more apparent. Therefore, we ex...
متن کاملEvaluation of the Edrophonium Challenge Test for Cervical Dystonia
Objective To examine whether or not an edrophonium challenge test is useful for diagnosing cervical dystonia. Patients We evaluated 10 patients with cervical dystonia and 10 with hemifacial spasms (disease controls). We administered edrophonium and saline in this double-blinded study. Before and after the injection, we recorded the participants' clinical signs using a video camera to assess the...
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Accurate ocular motility recordings were made of the saccadic responses of five patients with Eaton-Lambert syndrome (ELS). It was found that, contrary to common belief, the ocular motor system is affected. The saccades of ELS patients mimicked those of patients with myasthenia gravis (MG). Both groups exhibited hypometria and multiple, closely spaced saccades. Two patients demonstrated both sa...
متن کاملOperation for Blepharospasm.
BLEPHAROSPASM is an involuntary spasmodic but tonic contraction of the orbicularis oculi that may last a few seconds to a few minutes spaced by periods of relaxation. It tends to become progressive and bilateral and is often associated with spasms of other muscles innervated by the facial nerve. It is difficult to treat and is not subject to spontaneous resolution. The usual medical remedies (d...
متن کاملAnimal Models for Investigating Benign Essential Blepharospasm
The focal dystonia benign essential blepharospasm (BEB) affects as many as 40,000 individuals in the United States. This dystonia is characterized by trigeminal hyperexcitability, photophobia, and most disabling of the symptoms, involuntary spasms of lid closure that can produce functional blindness. Like many focal dystonias, BEB appears to develop from the interaction between a predisposing c...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2016
ISSN: 1662-453X
DOI: 10.3389/fnins.2016.00226